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msmu.pp.normalise

Normalise data in MuData object.

Parameters:

Name Type Description Default
mdata MuData

MuData object to normalise.

required
method str

Normalisation method to use. Options are 'quantile', 'median', 'total_sum (not implemented)'.

required
modality str

Modality to normalise. If None, all modalities at the specified level will be normalised.

required
layer str | None

Layer to normalise. If None, the default layer (.X) will be used.

None
fraction bool

If True, normalise within fractions. If False, normalise across all data. "fraction" yet supports fractionated TMT.

False

Returns:

Type Description
MuData

Normalised MuData object.